A reading room for our research record. Sialic acid biology, growth-factor literature, hydrolysis chemistry, and the published mechanism studies that informed MYSAO's R&D — laid out as education, not as advertising. 一间属于研究记录的「阅读室」。唾液酸生物学、生长因子文献、水解化学，以及指引 MYSAO 研发的已发表机理研究——以教育呈现，而非广告。
Singapore HSA cosmetic rules forbid product pages from making medical or therapeutic claims. We respect that line. The research below is real and we want our customers to be able to read it — but it is presented strictly as ingredient and biology education, separate from any product claim. 新加坡 HSA 化妆品法规禁止产品页面作出医疗或治疗主张。我们尊重这条边界。下方研究真实有据，我们希望客户能读到——但它严格作为成分与生物学教育呈现，与产品主张相互独立。
Edible Bird's Nest (EBN) is the salivary secretion of swiftlets in the genus Aerodramus and Collocalia, harvested for centuries in maritime Southeast Asia. EBN's most distinctive biochemical feature is its high content of N-acetylneuraminic acid (NANA), a member of the sialic acid family. 食用燕窝（EBN）是金丝燕属（Aerodramus、Collocalia）的唾液分泌物，在东南亚被采食数百年。其最显著的生化特征是富含 N-乙酰神经氨酸（NANA）——唾液酸家族的代表分子。
Sialic acids are nine-carbon acidic sugars that decorate the outermost surface of mammalian cell membranes. They participate in cell-to-cell recognition, immune signalling and barrier function. Human breast milk also carries sialylated oligosaccharides, where they support infant immunity and neuro-development. 唾液酸是九碳酸性糖，覆盖于哺乳动物细胞膜最外层，参与细胞识别、免疫信号与屏障功能。人乳同样含唾液酸化寡糖，对婴儿免疫与神经发育有支持作用。
References: Schauer R., Glycoconj J 2000;17:485–499. · Kobata A., Trends Glycosci Glycotechnol 2010;22:79–94. · ten Bruggencate SJM et al., Adv Nutr 2014;5:S65–S74.参考文献同左。
Native EBN is a tightly cross-linked glycoprotein. To present its bioactive sugar chains in a topically applicable form, the matrix must be cleaved without destroying the sugar moieties that carry the recognition signal. 原生燕窝是高度交联的糖蛋白基质。要把其生物活性糖链以外用形式释放，必须切断蛋白骨架，又不能破坏携带识别信号的糖基。
Conventional acidic hydrolysis at low pH is fast but tends to cleave glycosidic bonds, lowering sialic-acid yield. Patented controlled alkaline hydrolysis instead targets peptide bonds while preserving the α-2,3 / α-2,6-sialylated oligosaccharides intact, producing a fluid where the molar ratio of sialic acid to neutral hexose falls within an empirically optimised window (≈ 0.5–0.9). 传统酸性水解虽快，但易切断糖苷键，造成唾液酸损耗。专利受控碱性水解则针对肽键，同时保护 α-2,3 / α-2,6 唾液酸化寡糖完整，使唾液酸与中性己糖的摩尔比处于经验最优区间（约 0.5–0.9）。
| Step步骤 | Purpose目的 | Outcome结果 |
|---|---|---|
| Buffer-controlled alkaline cleavage缓冲碱性切割 | Open peptide backbone打开肽骨架 | Picogram-scale fragments皮克级片段 |
| Glycan preservation糖链保护 | Retain NANA chains保留 NANA 链 | Sialic/Hexose ratio 0.5–0.9唾液酸/己糖 比 0.5–0.9 |
| Membrane filtration膜分离 | Remove macro-residues去除大分子残渣 | Clear fluid, no scent payload清液，几乎无味 |
Reference: Method described in patent matrix US 10,610,537 B2; JP 6762027; CN 107778332; HK 1245050; MO J/002932. Method published in Fragrance Journal (Oct 2019).参考：专利矩阵 US 10,610,537 B2 / JP 6762027 / CN 107778332 / HK 1245050 / MO J/002932；方法发表于《Fragrance Journal》2019 年 10 月。
The figures below (">20× collagen", ">50% endogenous expression", FGF-7 / HGF / IGF-1 / EGF naming) describe ingredient-level in-vitro lab data, recorded in scientific literature for the SAO ingredient. Per SG compliance rules, these figures may not be transferred to or restated as efficacy claims for the MY SAO finished cosmetic product on the SG market. They appear here strictly within an "in-vitro lab data" educational frame, separated from any product claim. 下方数据（「>20× 胶原」「>50% 内源表达」、FGF-7 / HGF / IGF-1 / EGF）描述的是 SAO 成分层面的体外实验数据，源于学术文献。依新加坡合规规则，此类数据不得迁移或转述为 MY SAO 成品在新加坡市场的功效主张。其在此页面仅以「体外实验数据」的教育框架呈现，与任何产品主张相互独立。
Published in vitro mechanism studies on the hydrolyzed extract describe two parallel actions on dermal/follicular models. Both findings refer to ingredient behaviour in cellular assays — not to outcomes in a finished cosmetic product on living people.已发表的体外机理研究在真皮/毛囊模型中描述了水解精萃的两条并行作用。以下结论描述细胞实验中的成分行为，并非成品化妆品在人体上的功效。
In primary dermal fibroblast assays, the extract has been reported to upregulate Type I collagen synthesis (>20× control) and stimulate hyaluronic-acid (GAG) production. The reported effect supports an extracellular matrix able to anchor follicular structures.原代真皮成纤维细胞实验中，该精萃报告可上调 I 型胶原合成（>20×对照），并刺激透明质酸（GAG）合成。其结论支持构筑可锚定毛囊结构的细胞外基质。
In vitro fibroblast assay; published lab data.体外成纤维细胞实验，已发表实验数据。
In follicular co-culture models, the extract is reported to support endogenous expression of four growth-factor families (FGF-7, HGF, IGF-1, EGF) at >50% of unstimulated baseline. The extract does not contain these growth factors. It is reported to act as an ECM "architect" enabling expression rather than supplying them. 毛囊共培养模型中，该精萃报告可支持四类生长因子（FGF-7、HGF、IGF-1、EGF）的内源表达高于未刺激基线 50%。精萃本身不含这些生长因子——其报告角色是 ECM「架构师」，启动表达，而非外源补充。
In vitro follicular co-culture; published lab data.体外毛囊共培养，已发表实验数据。
"In vitro" means the experiment was run on isolated cells in a dish. Cellular results are biology, not consumer outcomes. They do not predict that a cosmetic containing the ingredient will produce equivalent results when applied to living scalps. We share these findings because customers asked for the underlying science — not as a claim about MYSAO. 「体外」即在培养皿的离体细胞上做的实验。细胞层面的结论属于生物学发现，并非消费者层面的疗效预测；并不意味着含此成分的化妆品在活人头皮上能达到同等结果。我们分享这些研究，是因为客户要求看到底层科学——不构成对 MYSAO 的功效主张。
Each of the four factors below has its own decades-deep research literature in dermatology and follicular biology. Brief educational summaries follow. The MYSAO product is a cosmetic and does not contain these growth factors.下列四种因子在皮肤学与毛囊生物学中均有数十年研究文献。下面是教育性简介。MYSAO 产品为化妆品，本身不含这些生长因子。
Fibroblast Growth Factor 7 / Keratinocyte Growth Factor. Studied in academic research literature on epithelial biology and hair shaft appearance.成纤维细胞生长因子 7 / 角质细胞生长因子。学术研究文献中涉及上皮生物学与发干外观的相关讨论对象。
Rubin JS et al., PNAS 1989;86:802–6.
Hepatocyte Growth Factor. Studied in academic research literature on paracrine signalling between dermal papilla and follicular epithelium.肝细胞生长因子。学术研究文献中涉及真皮乳头与毛囊上皮之间旁分泌信号的相关讨论对象。
Jindo T et al., J Invest Dermatol 1994;103:306–9.
Insulin-like Growth Factor 1. Studied in academic research literature on dermal papilla cell biology and age-related serum profile changes.类胰岛素生长因子 1。学术研究文献中涉及真皮乳头细胞生物学与血清水平随年龄变化的相关讨论对象。
Itami S et al., Endocrinology 1995;136:1276–82.
Epidermal Growth Factor. Discovered by Stanley Cohen, awarded the Nobel Prize in Physiology or Medicine 1986. Studied in academic research literature on epidermal homeostasis and skin barrier biology.表皮生长因子。由 Stanley Cohen 发现并获 1986 年诺贝尔生理或医学奖。学术研究文献中涉及表皮稳态与皮肤屏障生物学的相关讨论对象。
Cohen S, J Biol Chem 1962;237:1555–62.
Citations are educational. Their inclusion does not transfer the cited findings to the MYSAO finished product.文献仅作教育用途，不代表已发表结果可直接迁移至 MYSAO 成品。
Lab verification records, NMPA registration documents, toxicology safety reports.实验验证记录、NMPA 注册文件、毒理安全报告。
Why we built MYSAO. Why the firewall. Who is behind the brand.我们为何创立 MYSAO，为何设防火墙，团队背景。
Back to the homepage with the product, packs and ritual — kept commercial, kept compliant.回到首页：产品、套装与仪式——商业表达，合规呈现。
SCAP / ASAS · Mandatory Notice: There is no scientific proof that any product (except certain registered medicinal products) or service can retard hair loss or promote hair growth. Individual results may vary. SCAP / ASAS · 法定声明：没有科学证明任何产品（某些注册药品除外）或服务可以延缓脱发或促进毛发生长。实际效果因人而异。